Combination pain medication therapy in acute postoperative pain

The combination pain medication containing dexketoprofen 25 mg with tramadol 75 mg was effective, and more effective than either alone, in the treatment of acute post-op pain. Cochrane Database Syst Rev. 2016 Sep 22;9:CD012232.

Comment: To decrease opiod use, we are going to have to come up with other safe and effective pain medications. Using a combination of an NSAID with tramadol appears to work well, and is associated with a low rate of side-effects.